Methodologische Arbeiten II: Zellkultur, Zellbiologie
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DENKER, H.-W. and THIE, M.:
The regulatory function of the uterine epithelium for trophoblast attachment: experimental approaches.
In: Molecular, Cellular and Developmental Biology of Reproduction: Basic and Clinical Aspects (P.M. Motta, S.A. Nottola, G. Macchiarelli and S. Correr, Eds.).
Italian Journal of Anatomy and Embryology 106 (2 Supplement 2): 291-306, 2001.
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HOHN, H.-P., MÖLLER, W., HEYDER, J., DENKER, H.-W.:
Die Expression von Differenzierungsmarkern zeigt in BeWo-Chorionkarzinomzellen eine inverse Korrelation mit der Steifheit des Zytoskeletts.
(Abstr.) Verh. Anat. Ges. 96; Ann. Anat. 183 (Suppl.), 180, 2001.
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TINEL, H., DENKER, H.-W. and THIE, M.:
Calcium influx in human uterine epithelial RL95-2 cells triggers adhesiveness for trophoblast-like cells. Model studies on signalling events during embryo implantation.
Molecular Human Reproduction 6: 1119-1130 (2000). PubMed PDF-Download (1,00 MB)
THIE, M., DENKER H.-W.:
REM/AFM Untersuchungen an der freien Oberfläche von menschlichen Uterusepithelzellen - neue Einsichten in die Trophoblast-Uterusepithel-Interaktion in der Einleitungsphase der Embryo-Implantation.
(Abstr.) 29. Tagung der Deutschen Gesellschaft für Elektronenmikroskopie, Dortmund, 5.-10.09.1999. Eur J Cell Biol 78 (Suppl 50): 18 (1999).
HOHN, H.-P., MÖLLER, W., HEYDER, J., DENKER, H.-W.:
Differentiation of BeWo Choriocarcinoma Cells as Correlated with Biophysical Properties of the Cytoskeleton.
(Abstr.) Europ. J. Cell Biol. 78, (Suppl. 49), 54 (1999).
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HOHN, H.-P., MÖLLER, W., HEYDER, J., DENKER, H.-W.:
Differentiation of BeWo Choriocarcinoma Cells May be Correlated Inversely with Stiffness of the Cytoskeleton.
(Abstr.) Placenta 20, A.30 (1999).
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THIE, M.; RÖSPEL, R.; DETTMANN, W.; BENOIT, M.; LUDWIG, M.; GAUB, H.E. and DENKER, H.-W.:
Interactions between trophoblast and uterine epithelium:
monitoring of adhesive forces.
Human Reproduction 13, 3211-3219 (1998). PubMed PDF-Download (471 KB)
THIE, M., DETTMANN, W., RÖSPEL, R., BENOIT, M., LUDWIG, M., GAUB, H.E., DENKER, H.-W.:
Adhesion forces between confronted epithelia: uterine epithelium and trophoblast.
(Abstr.) 22. Jahrestagung der Deutschen Gesellschaft für Zellbiologie, Saarbrücken, 15.-19.03.1998, Eur J Cell Biol 75 (Suppl 48): 14 (1998)
THIE, M., RÖSPEL, R., DETTMANN, W., BENOIT, M., LUDWIG, M., GAUB, H.E. DENKER, H.-W.:
Attachment of trophoblast to uterine epithelium: direct measurements of adhesive forces with the atomic force microscope (AFM)
(Abstr.) Verh. Anat. Ges. 93, Anat. Anz./Annals of Anatomy 180, Suppl., 224-225 (1998)
HOHN, H.-P., DENKER, H.-W.:
Die Bedeutung mechanisch/struktureller Faktoren für die Zelldifferenzierung: Das „Tensegrity“-Konzept.
(Abstr.) Verh. Anat. Ges. 93, Anat. Anz./Annals of Anatomy 180, Suppl., 242-243 (1998)
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DETTMANN, W., THIE, M., BENOIT, M., RÖSPEL, R., LUDWIG, M., REISS, G., DENKER, H.-W., GAUB, H.E.:
Intercellular adhesion measurements with AFM.
(Abstr.) STM '97, 9th International Conference on Scanning Tunneling Microscopy / Spectroscopy and Related Techniques, Hamburg, July 20-25, 1997
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HOHN, H.-P., STEIH, U., DENKER, H.-W.:
A novel artificial substrate for cell culture:
effects of substrate flexibility/malleability on cell cell growth and morphology.
In Vitro Cell. Dev. Biol. 31A, 37-44 (1995). PubMed PDF-Download (973 KB, with kind permission of Springer, Heidelberg)
HOHN, H.-P., DENKER, H.-W.:
The role of cell shape for differentiation of choriocarcinoma cells on extracellular matrix.
Exp. Cell Res. 215, 40-50 (1994). PubMed
GRÜMMER, R., HOHN, H.-P., MAREEL, M.M., DENKER, H.-W.:
Adhesion and invasion of three human choriocarcinoma cell lines into human endometrium in a three-dimensional organ culture system.
Placenta 15, 411-429 (1994). PubMed
HOHN, H.-P., BOOTS, L.R., DENKER, H.-W., HÖÖK, M.:
Differentiation of human trophoblast cells in vitro stimulated by extracellular matrix.
In: Fetal Growth and the Placenta - From Implantation to Delivery. (H. Schneider, R. Bischof and R. Leiser, eds.) (Trophoblast Research, Vol. 7). University of Rochester Press, Rochester, NY. 181-200 (1993). PDF-Download (44,0 MB)
JOHN, N.J., LINKE, M. DENKER, H.-W.:
Quantitation of human choriocarcinoma spheroid attachment to uterine epithelial cell monolayer.
In Vitro Cell. Dev. Biol. 29A, 461-468 (1993). PubMed PDF-Download (3,16 MB, with kind permission of Springer, Heidelberg)
JOHN, N.J., LINKE, M., DENKER, H.-W.:
Retinoic acid decreases attachment of JAR choriocarcinoma spheroids to a human endometrial cell monolayer in vitro.
Placenta 14, 13-24 (1993). PubMed
HOHN, H.-P., PARKER, Jr. C.R., BOOTS, L.R., DENKER, H.-W., HÖÖK, M.:
Modulation of differentiation markers in human choriocarcinoma cells by extracellular matrix: on the role of a three-dimensional matrix structure.
Differentiation 51, 61-70 (1992). PubMed
HOHN, H.-P., MOOTZ, U. and DENKER, H.-W.:
Development of rabbit preimplantation blastocysts cultured with precultered endometrial tissue.
J. Reprod. Fert. 95, 409-420 (1992).
PubMed
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HOHN, H.-P., HÖÖK, M. und DENKER, H.-W.:
Zur Bedeutung der physikalischen Eigenschaften der extrazellulären Matrix für die Induktion der Differenzierung von Chorionkarzinomzellen.
(Abstr.) Verh. Anat. Ges. 87 (Anat. Anz. Suppl. 174), 62 (1992)
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DONNER, A., HOHN, H.-P. und DENKER, H.-W.:
Selektive Rezeptivität des Endometriums für Trophoblast-Invasion in einem Organkultur-Modell.
(Abstr.) Verh. Anat. Ges. 85 (Anat. Anz. Suppl. 170), 593-594 (1991)
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GRÜMMER, R. und DENKER, H.-W.:
Untersuchungen zum Invasionsverhalten dreidimensional wachsender Chorion-Karzinomzellen.
(Abstr.) Verh. Anat. Ges. 85 (Anat. Anz. Suppl. 170), 591-592 (1991)
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HOHN, H.-P., HÖÖK, M. and DENKER, H.-W.:
Differentiation of choriocarcinoma cells and normal trophoblast cells in response to extracellular matrix.
(Abstr.) IVth Meeting of the European Placenta Group (EPG) / Joint Meeting with the Rochester Tropholast Conference (RTC), Gwatt (Switzerland) 1991. Placenta 12, 400 (1991)
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JOHN, N.J., GRÜMMER, R. and DENKER, H.-W.:
Attachment of human choriocarcinoma cell spheroids to uterine epithelial monolayers: quantitative measurements of adhesion.
(Abstr.) Sixth Sympos. of the Section of Experimental Cancer Research (SEK) of the German Cancer Society, Heidelberg 1991. J. Cancer Res. Clin. Oncol. 117 (Suppl.), S 56 (1991).
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HOHN, H.-P., HÖÖK, M. and DENKER, H.-W.:
Induction of differentiation in choriocarcinoma cells by extracellular matrix: on the role of physical properties of the matrix.
(Abstr.) Sixth Sympos. of the Section of Experimental Cancer Research (SEK) of the German Cancer Society, Heidelberg 1991. J. Cancer Res. Clin. Oncol. 117 (Suppl.), S 49 (1991).
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HOHN, H.-P., DENKER, H.-W. und HÖÖK, M.:
Differenzierung von Chorionkarzinomzellen auf extrazellulärer Matrix.
(Abstr.) Verh. Anat. Ges. 84 (Anat. Anz. Suppl. 168), 49-50 (1991)
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HOHN, H.-P., HÖÖK, M., and DENKER, H.-W.:
Induction of differentiation in choriocarcinoma cells by extracellular matrix: On the role of physical properties of the matrix.
(Abstr.) Europ. J. Cell Biol., Suppl. 32 (Vol. 54), 48 (1991)
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GRÜMMER, R., HOHN, H.-P. and DENKER, H.-W.:
Choriocarcinoma cell spheroids: An in vitro model for the human trophoblast.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, pp. 97-111.
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HOHN, H.-P. and DENKER, H.-W.:
A three-dimensional organ culture model for the study of implantation of rabbit blastocyst in vitro.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, pp. 71-95.
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HOHN, H.-P., WINTERHAGER, E., BUSCH, L.C., MAREEL, M.M. and DENKER, H.-W.:
Rabbit endometrium in organ culture: Morphological evidence for progestational differentiation in vitro.
Cell Tissue Res. 257, 505-518 (1989).
PubMed
SpringerLink
GRÜMMER, R. and DENKER, H.-W.:
Investigations on the invasion of choriocarcinoma cells grown as spheroids.
(Abstr.) 3rd Meeting of the European Placenta Group, Dourdan (Frankreich) 1989. Placenta 10, 511-512 (1989)
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CLASSEN-LINKE, I., FRIEDRICH, J., GIESEN, U. and DENKER, H.-W.:
Histochemical studies on an endometrial in vitro model for embryo implantation in the rabbit.
(Abstr.) Ann. Meet. Deutsche Ges. f. Zellbiologie, 1989. Europ. J. Cell Biol. 48, Suppl. 26, 11 (1989)
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DENKER, H.-W., HOHN, H.-P., BÜKERS, A., CLASSEN-LINKE, I., DONNER, A. and WINTERHAGER, E.:
A novel endometrial organ culture system: observations on its use for studies of the initial phase of embryo implantation.
(Abstr.) In: Human Reproduction. Current Status/Future Prospect (Proceed. VIth World Congr. on Human Reproduction, Tokyo 1987, R. Iizuka and K. Semm, eds.). Amsterdam, etc.: Excerpta Medica, Elsevier Science Publ. (International Congress Series No. 768), 1988, p. 517
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HOHN, H.-P., PARKER, R., BOOTS, L., DENKER, H.-W. and HÖÖK, M.:
Induction of differentiation in choriocarcinoma cells by placental extracellular matrix.
(Abstr.) Ann. Meet. Deutsche Ges. f. Zellbiologie, München 1988. Europ. J. Cell Biol. 46 , Suppl. 22, 32 (1988)
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BÜKERS, A., HOHN, H.-P., DENKER, H.-W.:
Lectin histochemical evaluation of an in-vitro model for trophoblast invasion.
(Abstr.) International Symposium "Lectins and Glycoconjugates in Oncology. Structure, Function, Clinical Application", Göttingen / FR Germany, 4-5 December 1987.
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DENKER, H.-W., HOHN, H.-P. und WINTERHAGER, E.:
Dreidimensionale Aggregate von Chorionkarzinomzellen als ein In-vitro-Modell für den invasiven Trophoblasten.
Verh. Anat. Ges. 81 (Lübeck 1986), Anat. Anz. Suppl. 162, 499-500 (1987). PDF-Download (694 KB)
HOHN, H.-P., DONNER, A. and DENKER, H.-W.:
Specific receptivity of rabbit endometrium for attachment of trophoblast but not of tumor cells in vitro.
(Abstr.) J. Cell Biol. 105, 306a (1987)
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HOHN, H.-P., DONNER, A. and DENKER, H.-W.:
Evaluation of an in vitro model for embryo implantation: Selective receptivity of rabbit endometrium for trophoblast attachment.
(Abstr.) Ann. Meet. Deutsche Ges. Zellbiologie, Tübingen 1986. Europ. J. Cell Biol. 39, Suppl. 12, 18 (1985)
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HOHN, H.-P., DENKER, H.-W. and BUSCH, L.C.:
Endometrium in organ culture and coculture with blastocysts: development of an in vitro model for embryo implantation.
(Abstr.) 7th European Anatomical Congress, Innsbruck 1984. Acta anat. 120, 33 (1984)
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DENKER, H.-W., BUSCH, L.C. and KÜHNEL, W.:
Endometrial organ culture: development of an in-vitro model for embryo implantation.
(Abstr.) 4. Arbeitstagung der Anatomischen Gesellschaft, Würzburg 1983. Anat. Anz. 156, 142 (1984)
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DENKER, H.-W., HOHN, H.-P. and WINTERHAGER, E.:
Confrontation of rabbit blastocysts and endometrium in organ culture.
(Abstr.) XXII Annual Meeting of the Cell, Tissue and Organ Culture Study Group (C.T.O.C.), Noordwijkerhout, May 1984
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HOHN, H.-P., BUSCH, L.C. and DENKER, H.-W.:
Endometrium in organ culture: a model host tissue for studies of trophoblast invasion.
(Abstr.) Annual Meeting, Deutsche Ges. Zellbiologie, Marburg 1984. Europ. J. Cell Biol. 33, Suppl. 5, 17 (1984)
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DENKER, H.-W., BUSCH, L.C. and KÜHNEL, W.:
Development of an in-vitro model for embryo implantation and trophoblast invasion.
(Abstr.) XXI Annual Meeting of the Cell, Tissue and Organ Culture Study Group (CTOC) affiliated with the International Union Against Cancer (U.I.C.C.) on "In Vitro Methods for Evaluation of Anticancer Therapy Effects", Milano, May 1983
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