Original-Publikationen und Buchbeiträge
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DENKER, H.-W.:
Embryoids, models, embryos? We need to take a new look at legal norms concerning the beginning of organismic development.
Molec. Hum. Reprod. 30(1): gaad047 (2024). DOI: 10.1093/molehr/gaad047
PubMed
MHR
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DENKER, H.-W.:
Stem Cell-Derived Organoids, Embryoids, and Embryos: Advances in Organismic Development In Vitro Force Us to Re-Focus on Ethical and Legal Aspects of Model Choice.
Organoids 2: 231-238 (2023). DOI: 10.3390/organoids2040018
Organoids Website
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DENKER, H.-W.:
Wir brauchen eine Neudefinition des Begriffs "Embryo".
Deutsches Ärzteblatt 120 (33-34): A-1383 / B-1191 (21. August 2023).
Deutsches Ärzteblatt
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SHENG, G., THOMPSON, E., NEWGREEN, D., DENKER, H.-W.:
Twenty Years on for The Epithelial-Mesenchymal Transition International Association (TEMTIA): An Interview with Co-Founders Erik Thompson and Donald Newgreen.
Cells Tissues Organs 211(2): 252-260 (2022). DOI: 10.1159/000518250
PubMed
CTO Website (free access)
DENKER, H.-W.:
Autonomy in the Development of Stem Cell-Derived Embryoids:
Sprouting Blastocyst-Like Cysts, and Ethical Implications.
Cells 10: 1461 (2021) (Open Access). DOI: 10.3390/cells10061461
PubMed
Cells Website
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DENKER, H.-W.:
Rise of the rabbit model for implantation research. A commemoration of the scientific work of Bent G. Boving (1920-2019).
Biology of Reproduction 102 (6): 1170-1176 (2020). DOI: 10.1093/biolre/ioaa038
PubMed
BOR
BOR (free access)
DENKER, H.-W.:
Recent embryo twinning data prompt reconsideration of theories on a crucial role of segregation of oocyte cytoplasmic constituents in mammals.
(Kommentar zu: CASSER, E., WDOWIK, S., ISRAEL, S., WITTEN, A., SCHLATT, S., NORDHOFF, V., BOIANI, M.: Differences in blastomere totipotency in 2-cell mouse embryos are a maternal trait mediated by asymmetric mRNA distribution. Molec. Hum. Reproduct. 25/11, 729-744, 2019. DOI: 10.1093/molehr/gaz051)
Molec. Hum. Reprod. 26: 193-198 (2020). DOI: 10.1093/molehr/gaaa005
PubMed
MHR
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DENKER, H.-W.:
Embryonen, Embryoide, Gastruloide... Ethische Aspekte zur Selbstorganisation und zum Engineering von Stammzellkolonien und Embryonen.
In: M. Rothhaar, M. Hähnel, R. Kipke (Eds.): Der manipulierbare Embryo. Potentialitäts- und Speziesargumente auf dem Prüfstand. Münster: Mentis (Brill), 2018, pp. 15-47. DOI: 10.30965/9783957438393_003 (Open Access)
Mentis (Brill) (Open Access)
Google Scholar
Abstract (40 KB)
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DENKER, H.-W.:
Self-Organization of Stem Cell Colonies and of Early Mammalian Embryos: Recent Experiments Shed New Light on the Role of Autonomy vs. External Instructions in Basic Body Plan Development.
Cells 5(4): E39 (2016) (Open access). DOI: 10.3390/cells5040039
PubMed
Cells Website
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DENKER, H.-W.:
Implantation: Cell biology of embryo penetration route revisited.
(Kommentar zu: UCHIDA, H. et al.: How to create an embryo penetration route. Am. J. Reprod. Immunol. 75(3): 326-332, 2016. DOI: 10.1111/aji.12476)
Am. J. Reprod. Immunol. 76(6): 429-431 (2016). DOI: 10.1111/aji.12591
PubMed
AJRI
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Summary (68 KB)
DENKER, H.-W.:
A Quest for Refocussing Stem Cell Induction Strategies: How to Deal with Ethical Objections and Patenting Problems.
In: M. Prasad and P. Di Nardo (Eds.): Innovative Strategies in Tissue Engineering. (River Publishers Series in Research and Business Chronicles: Biotechnology and Medicine; Vol. 2; A. Vertes, P. Di Nardo and P. Rameshwar, Ser.-Eds.) Aalborg, Denmark: River Publishers, 2015, pp. 117-134. DOI: 10.13052/rp-9788793237100
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River Publishers
River Publishers (Open Access)
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DENKER, H.-W.:
Stem Cell Terminology and 'Synthetic' Embryos: A New Debate on Totipotency, Omnipotency, and Pluripotency and How It Relates to Recent Experimental Data
Cells Tissues Organs 199: 221-227 (2014).
PubMed
CTO Website (free access)
DENKER, H.-W.:
Comment on G. Herranz: The timing of monozygotic twinning: a criticism of the common model. Zygote (2013).
Zygote 23: 312-314 (2015).
PubMed
Zygote
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DENKER, H.-W.:
Time to reconsider stem cell induction strategies.
Cells 1: 1293-1312 (2012) (Open Access).
PubMed
Cells Website
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LITTWIN, T., DENKER, H.-W.:
Segregation during cleavage in the mammalian embryo? A critical comparison of whole-mount/CLSM and section immunohistochemistry casts doubts on segregation of axis-relevant leptin domains in the rabbit.
Histochemistry and Cell Biology 135: 553-570 (2011).
PubMed
SpringerLink
MARANCA-HÜWEL, B., DENKER, H.-W.:
Epithelial-mesenchymal transition in rhesus monkey embryonic stem cell colonies: the role of culturing conditions.
In Vitro Cell. Dev. Biol. - Animal 46(6): 516-528 (2010).
PubMed PDF-Download (951 KB; Bitte beachten Sie die Urheberrechtshinweise der SIVBThis material has been published in In Vitro Cell. Dev. Biol. - Animal 46(6): 516-528 (2010), the only accredited archive of the content that has been certified and accepted after peer review. Copyright and all rights therein are retained by the Society for In Vitro Biology. This material may not be copied or e-posted without explicit permission of the copyright owner.
For more information about Reproduction Permission for this article, please visit the SIVB website by clicking on the link above or anywhere on this infobox.!)
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DENKER, H.-W.:
Induced pluripotent stem cells: How to deal with the developmental potential.
Reproductive BioMedicine Online 19 Suppl. 1: 34-37 (2009).
PubMed
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RBMOnline
DENKER, H.-W.:
Totipotency/pluripotency and patentability.
Stem Cells 26: 1656-1657 (2008). PubMed Stem Cells PDF-Download (14,4 KB)
DENKER, H.-W.:
Human embryonic stem cells:
The real challenge for research as well as for bioethics is still ahead of us.
Cells Tissues Organs 187: 250-256 (2008).
PubMed
PDF-Download (155 KB)
DENKER, H.-W., BEHR, R., HENEWEER, C., VIEBAHN, C., THIE, M.:
Epithelial-mesenchymal transition in rhesus monkey embryonic stem cell colonies: a model for processes involved in gastrulation?
Cells Tissues Organs 185: 48-50 (2007). PubMed PDF-Download (162 KB)
LEI, T., HOHN, H.-P., BEHR, R., DENKER, H.-W.:
Influences of Extracellular Matrix and of Conditioned Media on Differentiation and Invasiveness of Trophoblast Stem Cells.
Placenta 28: 14-21 (2007). PubMed
DENKER, H.-W.:
Potentiality of embryonic stem cells: an ethical problem even with alternative stem cell sources.
Journal of Medical Ethics 32: 665-671 (2006). PubMed PDF-Download (131 KB)
DENKER, H.-W.:
Totipotenz – Omnipotenz – Pluripotenz.
Ausblendungsphänomene in der Stammzelldebatte: Indikatoren für den Konflikt zwischen Norm- und Nutzenkultur?
In: Th. S. Hoffmann, W. Schweidler (Eds.): Normkultur versus Nutzenkultur. Über kulturelle Kontexte von Bioethik und Biorecht. Walter de Gruyter, Berlin/New York, 2006, pp. 249-272.
De Gruyter
Google Books
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DENKER, U., DENKER, H.-W.:
Embryonale Stammzellforschung: Aufklärung notwendig. Problematik der informierten Zustimmung der Spender.
Dtsch. Ärztebl.102: A892-A893 (2005). PDF-Download (56,7 KB)
HENEWEER, C., SCHMIDT, M., DENKER, H.-W., THIE, M.:
Molecular mechanisms in uterine epithelium during trophoblast binding:
the role of small GTPase RhoA in human uterine Ishikawa cells.
Journal of Experimental & Clinical Assisted Reproduction (JECAR), 2:4 (09 Mar 2005) (Open Access). DOI: 10.1186/1743-1050-2-4
PubMed
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BEHR, R., HENEWEER, C., VIEBAHN, C., DENKER, H.-W., THIE, M.:
Epithelial-mesenchymal transition in colonies of rhesus monkey embryonic stem cells: a model for processes involved in gastrulation.
Stem Cells 23: 805-816 (2005). PubMed PDF-Download (559 KB)
DENKER, H.-W.:
Die Potenz von menschlichen ES-Zellen als Argument gegen ihre Patentierbarkeit.
Jahrbuch für Wissenschaft und Ethik, Vol. 9 (L. Honnefelder u. C. Streffer, eds.).
Berlin/New York: Walter de Gruyter, 2004, pp. 367-371. PDF-Download (8,75 MB)
English Abstract (0,99 MB): The developmental potential of human embryonic stem cells argues against their patentability
DENKER, H.-W.:
Early human development: New data raise important embryological and ethical questions relevant for stem cell research.
Naturwissenschaften 91: 1-21 (2004). PubMed PDF-Download (853 KB)
HENEWEER, C., ADELMANN, H.G., KRUSE, L.H., DENKER, H.-W., THIE, M.:
Human Uterine Epithelial RL95-2 Cells Reorganize Their Cytoplasmic Architecture with Respect to Rho Protein and F-Actin in Response to Trophoblast Binding.
Cells Tissues Organs 175: 1-8 (2003). PubMed PDF-Download (180 KB)
DENKER, H.-W.:
Totipotenz oder Pluripotenz? Embryonale Stammzellen, die Alleskönner.
Dtsch. Ärztebl. 100 (Heft 42): A 2728-2730 (2003).
aerzteblatt.de
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GUSTAFSSON, E., ASZÓDI, A., ORTEGA, N., HUNZIKER, E.B., DENKER, H.-W., WERB, Z. and FÄSSLER, R.:
Role of collagen type II and perlecan in skeletal development.
Ann. N. Y. Acad. Sci. 995 (Tissue remodelling; eds: M. Nilsen-Hamilton, Z. Werb and E. Keshet): 140-150 (2003).
PubMed
HOHN, H.-P., DONNER, A.J. and DENKER, H.-W.:
Endometrial receptivity: Selective adhesion competence of rabbit uterine epithelium for trophoblast but not for various tumor cells.
Cells Tissues Organs 173: 204-216 (2003). PubMed PDF-Download (720 KB)
DENKER, H.-W.:
Embryonale Stammzellen als entwicklungsbiologisches Modell: Frühembryonale Musterbildung und Totipotenz.
In: Die Frühphase der Entwicklung des Menschen. Embryologische und ethische Aspekte. (G. Rager /A. Holderegger, Eds.) (Reihe: Herausforderung und Besinnung, Band 19). Universitätsverlag Freiburg/Schweiz, ISBN 3-7278-1416-0 (distributed by: Academic Press, Fribourg/Switzerland), 2003, pp. 23-71. PDF-Download (104 MB)
THIE, M. and DENKER, H.-W.:
In vitro studies on endometrial adhesiveness for trophoblast: cellular dynamics in uterine epithelial cells.
Cells Tissues Organs 172: 237-252 (2002). PubMed PDF-Download (835 KB)
HOHN, H.-P. and DENKER, H.-W.:
Experimental modulation of cell-cell adhesion, invasiveness and differentiation in trophoblast cells.
Cells Tissues Organs 172: 218-236 (2002). PubMed PDF-Download (391 KB)
HENEWEER, C., KRUSE, L.H., KINDHÄUSER, F., SCHMIDT, M., JAKOBS, K.H., DENKER, H.-W. and THIE, M.:
Adhesiveness of human uterine epithelial RL95-2 cells to trophoblast: Rho protein regulation.
Molecular Human Reproduction 8: 1014-1022 (2002). PubMed PDF-Download (2,01 MB)
DENKER; H.-W.:
Forschung an embryonalen Stammzellen: Eine Diskussion der Begriffe Totipotenz und Pluripotenz.
In: Stammzellenforschung und therapeutisches Klonen. (F.S. Oduncu, U. Schroth und W. Vossenkuhl, Eds.)
Göttingen: Vandenhoeck und Ruprecht, 2002, pp. 19-35. PDF-Download (35,1 MB)
DENKER, H.-W. and THIE, M.:
The regulatory function of the uterine epithelium for trophoblast attachment: experimental approaches.
In: Molecular, Cellular and Developmental Biology of Reproduction: Basic and Clinical Aspects (P.M. Motta, S.A. Nottola, G. Macchiarelli and S. Correr, Eds.).
Italian Journal of Anatomy and Embryology 106 (2 Supplement 2): 291-306, 2001.
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PubMed
TINEL, H., DENKER, H.-W. and THIE, M.:
Calcium influx in human uterine epithelial RL95-2 cells triggers adhesiveness for trophoblast-like cells. Model studies on signalling events during embryo implantation.
Molecular Human Reproduction 6: 1119-1130 (2000). PubMed PDF-Download (1,00 MB)
HOHN, H.-P., LINKE, M. and DENKER, H.-W.:
Adhesion of trophoblast to uterine epithelium as related to the state of trophoblast differentiation: in vitro studies using cell lines.
Mol. Reprod. Dev. 57: 135-145 (2000). PubMed PDF-Download (33,0 MB)
DENKER, H.-W.:
Structural dynamics and function of early embryonic coats.
Cells Tissues Organs 166: 180-207 (2000). PubMed PDF-Download (1,60 MB)
DENKER, H.-W.:
Embryonale Stammzellen und ihre ethische Wertigkeit: Aspekte des Totipotenz-Problems.
In: Jahrbuch für Wissenschaft und Ethik Band 5 (L. Honnefelder und C. Streffer, Hg.). de Gruyter, Berlin - New York, 2000, pp. 291-304. PDF-Download (16,6 MB)
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DENKER, H.-W.:
Embryonic stem cells: An exciting field for basic research and tissue engineering, but also an ethical dilemma?
Cells Tissues Organs 165: 246-249 (1999).
PDF-Download (188 KB)
PubMed
CTO Website (free access)
THIE, M.; RÖSPEL, R.; DETTMANN, W.; BENOIT, M.; LUDWIG, M.; GAUB, H.E. and DENKER, H.-W.:
Interactions between trophoblast and uterine epithelium:
monitoring of adhesive forces.
Human Reproduction 13, 3211-3219 (1998). PubMed PDF-Download (471 KB)
HUCH, G.; HOHN, H.-P. and DENKER, H.-W.:
Identification of differentially expressed genes in human trophoblast cells by differential-display RT-PCR.
Placenta 19, 557-567 (1998). PubMed
HOHN, H.-P.; LINKE, M.; UGELE, B. and DENKER, H.-W.:
Differentiation markers and invasiveness: Discordent regulation in normal trophoblast and chorion carcinoma cells.
Exptl. Cell Res. 244, 249-258 (1998). PubMed
BIERMANN, L.; GABIUS, H.-J. and DENKER, H.-W.:
Neoglycoprotein-binding sites (endogenous lectins) in the Fallopian tube, uterus and blastocyst of the rabbit during the preimplantation phase and implantation.
Acta Anat. 160, 159-171 (1997). PubMed PDF-Download (24,3 MB)
WEIDEMANN, J., HOHN, H.-P., HILTNER, J., TOCHTERMANN, K., TRESP, C., BOZINOV, D., VENJAKOB, K., FREUND, A., REUSCH, B. and DENKER, H.-W.:
A hypermedia tutorial for cross sectional anatomy: HyperMed.
Acta Anat. 158, 133-142 (1997). PubMed PDF-Download (30,1 MB)
THIE, M., HERTER, P., POMMERENKE, H., DÜRR, F., SIECKMANN, F., NEBE, B., RYCHLY, J. and DENKER, H.-W.:
Adhesiveness of the free surface of a human endometrial monolayer for trophoblast as related to actin cytoskeleton.
Molecular Human Reproduction 3, 275-283 (1997). PubMed PDF-Download (607 KB)
THIE, M. and DENKER, H.-W.:
Endometrial receptivity for trophoblast attachment: Model studies using cell lines.
In: Microscopy for Reproduction and Development: A Dynamic Approach (P.M. Motta, ed.). Antonio Delfino Editore, Rome, 1997, pp. 241-249. PDF-Download (30,0 MB)
THIE, M., FUCHS, P., BUTZ, S., SIECKMANN, F., HOSCHÜTZKY, H., KEMLER, R., DENKER, H.-W.:
Adhesiveness of the apical surface of uterine epithelial cells:
the role of junctional complex integrity.
Europ. J.Cell Biol. 70, 221-232 (1996). PubMed PDF-Download (7,88 MB)
THIE, M., FUCHS, P., DENKER, H.-W.:
Epithelial cell polarity and embryo implantation in mammals.
Int. J. Dev. Biol. 40, 389-393 (1996). PubMed PDF-Download (1,81 MB)
HOHN, H.-P., GRÜMMER, R., BOSSERHOFF, S., GRAF-LIGNAU, S., REUSS, B., BÄCKER, C., DENKER, H.-W.:
The role of matrix contact and of cell-cell interactions in choriocarcinoma cell differentiation.
Europ. J.Cell Biol. 69, 76-85 (1996). PubMed PDF-Download (6,86 MB)
POST, H., HOHN, H.-P., MAYSAMI, M., MÜTER, S., DENKER, H.-W.:
A new simple method for conversation and demonstration of body sections for teaching clinically oriented courses in gross anatomy.
J. Anat. 189, 685-688 (1996). PubMed PDF-Download (1,23 MB)
TOCHTERMANN, K., TRESP, C., HILTNER, J., REUSCH, B., WEIDEMANN, J., HOHN, H.-P., DENKER, H.-W. and FREUND, A.:
HyperMed: a hypermedia system for anatomical education.
In: P. Carlson and F. Makedon (eds.): Educational Multimedia and Hypermedia, 1996 (Proceedings of ED-MEDIA 96 - World Conference on Educational Multimedia and Hypermedia, Boston (Mass., USA), Juni 17-22, 1996. Association for the Advancement of Computing in Education (AACE), Charlottesville (VA, USA), 1996, pp. 667-672. PDF-Download (240 KB)
THIE, M., HARRACH-RUPRECHT, B., SAUER, H., FUCHS, P., ALBERS, A., DENKER, H.-W.:
Cell adhesion to the apical pole of epithelium: a function of cell polarity.
Europ. J.Cell Biol. 66, 180-191 (1995). PubMed PDF-Download (8,49 MB)
ALBERS, A., THIE, M., HOHN, H.-P., DENKER, H.-W.:
Differential expression and localization of integrins and CD44 in the membrane domains of human uterine epithelial cells during the menstrual cycle.
Acta Anatomica 153, 12-19 (1995). PubMed PDF-Download (15,3 MB)
HOHN, H.-P., HUCH, G., TLOLKA, U., DENKER, H.-W.:
Differential Expression of CD44 in rabbit uterine epithelium during early pregnancy.
Acta Anatomica 152, 185-194 (1995). PubMed PDF-Download (16,8 MB)
HOHN, H.-P., STEIH, U., DENKER, H.-W.:
A novel artificial substrate for cell culture:
effects of substrate flexibility/malleability on cell cell growth and morphology.
In Vitro Cell. Dev. Biol. 31A, 37-44 (1995). PubMed PDF-Download (973 KB, with kind permission of Springer, Heidelberg)
DENKER, H.-W.:
Cell biological views of embryo implantation (A Review).
Turkish J. of Medical Sciences, Suppl., 1-12 (1995). PDF-Download (29,1 MB)
HOHN, H.-P., DENKER, H.-W.:
The role of cell shape for differentiation of choriocarcinoma cells on extracellular matrix.
Exp. Cell Res. 215, 40-50 (1994). PubMed
GRÜMMER, R., HOHN, H.-P., MAREEL, M.M., DENKER, H.-W.:
Adhesion and invasion of three human choriocarcinoma cell lines into human endometrium in a three-dimensional organ culture system.
Placenta 15, 411-429 (1994). PubMed
DENKER, H.-W.:
Endometrial receptivity: Cell biological aspects of an unusual epithelium. A review.
Ann. Anat. 176, 53-60 (1994). PubMed PDF-Download (5,57 MB)
BRÖKELMANN, J., DENKER, H.-W.:
Weibliche Geschlechtsorgane.
In: Benninghoff Anatomie. Makroskopische Anatomie, Embryologie und Histologie des Menschen, Band 2: Niere, Reproduktionsorgane, endokrine Drüsen, Nervensystem, Sinnesorgane, Haut. (D. Drenckhahn und W. Zenker, eds.), Kapitel 13.4; 15. Auflage. München: Urban & Schwarzenberg, 1994, pp. 115-163.
THIE, M., ALBERS, A., and DENKER, H.-W.:
Endometrial receptivity: cell biological aspects.
In: Mori, T., Aono, T., Tominaga, T. and Hiroi, H. (eds.): Perspectives on Assisted Reproduction (Serono Symposia Series "Frontiers in Endocrinology", Vol. 4). Ares-Serono Symposia, Christengraf, Rome, 1994, pp. 331-337. PDF-Download (2,98 MB)
DENKER, H.-W.:
Cell biology of endometrial receptivity and of trophoblast-endometrial interactions.
In: Endocrinology of Embryo-Endometrium Interactions (S.R. Glasser, J. Mulholland and A. Psychoyos, eds.) New York: Plenum Press, 1994, pp. 17-32. DOI: 10.1007/978-1-4615-1881-5_3
SpringerLink
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DENKER, H.-W.:
Implantation: A cell biological paradox.
J. Exp. Zool. 266, 541-558 (1993). PubMed PDF-Download (75,9 MB)
HOHN, H.-P., BOOTS, L.R., DENKER, H.-W., HÖÖK, M.:
Differentiation of human trophoblast cells in vitro stimulated by extracellular matrix.
In: Fetal Growth and the Placenta - From Implantation to Delivery. (H. Schneider, R. Bischof and R. Leiser, eds.) (Trophoblast Research, Vol. 7). University of Rochester Press, Rochester, NY. 181-200 (1993). PDF-Download (44,0 MB)
JOHN, N.J., LINKE, M. DENKER, H.-W.:
Quantitation of human choriocarcinoma spheroid attachment to uterine epithelial cell monolayer.
In Vitro Cell. Dev. Biol. 29A, 461-468 (1993). PubMed PDF-Download (3,16 MB, with kind permission of Springer, Heidelberg)
JOHN, N.J., LINKE, M., DENKER, H.-W.:
Retinoic acid decreases attachment of JAR choriocarcinoma spheroids to a human endometrial cell monolayer in vitro.
Placenta 14, 13-24 (1993). PubMed
HOHN, H.-P., PARKER, Jr. C.R., BOOTS, L.R., DENKER, H.-W., HÖÖK, M.:
Modulation of differentiation markers in human choriocarcinoma cells by extracellular matrix: on the role of a three-dimensional matrix structure.
Differentiation 51, 61-70 (1992). PubMed
HOHN, H.-P., MOOTZ, U. and DENKER, H.-W.:
Development of rabbit preimplantation blastocysts cultured with precultered endometrial tissue.
J. Reprod. Fert. 95, 409-420 (1992).
PubMed
Reproduction PDF-Download
MITCHELL, J.A. and DENKER, H.-W.:
Endometrial arylamidase activitiy in the guinea pig: changes during the ostrous cycle, decidualization and ovarian steroid hormone treatment.
Comp. Biochem. Physiol. 99B, 709-712 (1991). PubMed
FISCHER, B., MOOTZ, U., DENKER, H.-W., LAMBERTZ, M. and BEIER, H.M.:
The dynamic structure of rabbit blastocyst coverings. III. Transformation of coverings under non-physiological developmental conditions.
Anat. Embryol. 183, 17-27 (1991).
PubMed
SpringerLink
MARX, M., WINTERHAGER, E. and DENKER, H.-W.:
Penetration of the basal lamina by processes of uterine epithelial cells during implantation in the rabbit.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, pp. 417-430.
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SpringerLink
HOCHFELD, A., BEIER, H.M. and DENKER, H.-W.:
Changes of intermediate filament protein localization in endometrial cells during early pregnancy of rabbits.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, pp. 357-374.
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SpringerLink
WINTERHAGER, E. and DENKER, H.-W.:
Changes in lipid organization of uterine epithelial cell membranes at implantation in the rabbit.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, pp. 323-338.
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SpringerLink
CLASSEN-LINKE, I. and DENKER, H.-W.:
Preparation of rabbit uterine epithelium for trophoblast attachment: Histochemical changes in the apical and lateral membrane compartment.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, pp. 307-322.
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SpringerLink
BÜKERS, A., FRIEDRICH, J., NALBACH, B.P. and DENKER, H.-W.:
Changes in lectin binding patterns in rabbit endometrium during pseudopregnancy, early pregnancy and implantation.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, pp. 285-305.
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SpringerLink
GRÜMMER, R., HOHN, H.-P. and DENKER, H.-W.:
Choriocarcinoma cell spheroids: An in vitro model for the human trophoblast.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, pp. 97-111.
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SpringerLink
HOHN, H.-P. and DENKER, H.-W.:
A three-dimensional organ culture model for the study of implantation of rabbit blastocyst in vitro.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, pp. 71-95.
PDF-Download (35,8 MB, with kind permission of Springer Science and Business Media)
SpringerLink
DENKER, H.-W.:
Trophoblast-endometrial interactions at embryo implantation: A cell biological paradox.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, pp. 3-29.
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DENKER, H.-W. and APLIN, J.:
Preface.
In: Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. (H.-W. Denker and J.D. Aplin, eds.) (Trophoblast Research, Vol. 4). New York and London: Plenum Medical Book Comp., 1990, p. vii.
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BÜKERS, A. und DENKER, H.-W.:
Lektinhistochemische Charakterisierung von Kaninchenendometrium in vivo und in vitro - eine vergleichende Studie.
Verh. Anat. Ges. 83 (Anat. Anz. Suppl. 166), 415-416 (1990).
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HOHN, H.-P., WINTERHAGER, E., BUSCH, L.C., MAREEL, M.M. and DENKER, H.-W.:
Rabbit endometrium in organ culture: Morphological evidence for progestational differentiation in vitro.
Cell Tissue Res. 257, 505-518 (1989).
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DENKER, H.-W., HOHN, H.-P. and BÜKERS, A.:
Investigations on the cell biology of embryo implantation.
In: Reproductive Biology and Medicine (A.F. Holstein, K.D. Voigt and D. Grässlin, eds.) Berlin: Diesbach Verlag 1989, pp. 224-238. PDF-Download (32,4 MB)
LEISER, R. and DENKER, H.-W.:
The dynamic structure of rabbit blastocyst coverings. II. Ultrastructural evidence for a role of the trophoblast in neozona formation.
Anat. Embryol. 179, 129-134 (1988).
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MITCHELL, J.A. and DENKER, H.-W.:
Implantation-induced changes in uterine arylamidase localization in the rabbit, rat, hamster and guinea-pig.
J. Reprod. Fert. 83, 355-364 (1988).
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WINTERHAGER, E., BRÜMMER, F., DERMIETZEL, R., HÜLSER, D.F. and DENKER, H.-W.:
Gap junction formation in rabbit uterine epithelium in response to embryo recognition.
Dev. Biol. 126, 203-211 (1988). PubMed PDF (Deutsche Nationalbibliothek)
DENKER, H.-W.:
Implantation: Recent approaches to understand a cell biological paradox.
In: Human Reproduction. Current Status/Future Prospect (Proceed. VIth World Congr. on Human Reproduction, Tokyo 1987) (R. Iizuka and K. Semm, eds.) Amsterdam, etc.: Excerpta Medica, Elsevier Science Publ. (International Congress Series Nr. 768), 1988, pp. 237-240. PDF-Download (1,86 MB)
WINTERHAGER, E., LEISER, R., DENKER, H.-W.:
Lipiddomänen der Plasmamembran im Uterusepithel von Kaninchen zum Zeitpunkt der Implantation. Eine gefrierbruch-zytochemische Untersuchung.
XXXVII Sympos. Ges. f. Histochemie, Gargellen 1986. Acta histochem., Suppl. 36, 395-398 (1988). PubMed
CLASSEN-LINKE, I., DENKER, H.-W. and WINTERHAGER, E.:
Apical plasma membrane-bound enzymes of rabbit uterine epithelium: Pattern changes during the periimplantation phase.
Histochemistry 87, 517-529 (1987). PubMed PDF-Download (5,97 MB, with kind permission of Springer, Heidelberg)
MITCHELL, J.A., DRIESSEN, G., SCHEIDT, H. and DENKER, H.-W.:
Changes in intraconceptus pressure in the rabbit during days 7 - 10 of pregnancy.
Biol. Reprod. 36, 669-675 (1987).
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DENKER, H.-W., HOHN, H.-P. und WINTERHAGER, E.:
Dreidimensionale Aggregate von Chorionkarzinomzellen als ein In-vitro-Modell für den invasiven Trophoblasten.
Verh. Anat. Ges. 81 (Lübeck 1986), Anat. Anz. Suppl. 162, 499-500 (1987). PDF-Download (694 KB)
WINTERHAGER, E., DERMIETZEL, R., BRÜMMER, F. und DENKER, H.-W.:
Immunhistochemischer Nachweis des 26k-Proteins der gap junctions im Uterusepithel des Kaninchens in Abhängigkeit von der Reproduktionsphase.
Verh. Anat. Ges. 81 (Lübeck 1986), Anat. Anz. Suppl. 162, 503-504 (1987). PDF-Download (881 KB)
DENKER, H.-W. and TYNDALE-BISCOE, C.H.:
Embryo implantation and proteinase activities in a marsupial (Macropus eugenii): Histochemical patterns of proteinases in various gestational stages.
Cell Tissue Res. 246, 279-291 (1986).
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DENKER, H.-W.:
Embryo implantation and proteinase activities in a marsupial (Macropus eugenii): II. Preliminary characterization of proteinases.
Manuscript (1986). DOI: 10.13140/RG.2.2.21151.18089
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DENKER, H.-W.:
Epithel-Epithel-Interaktionen bei der Embryo-Implantation: Ansätze zur Lösung eines zellbiologischen Paradoxons. (Hauptreferat).
Verh. Anat. Ges. 80 (Prag 1985), Anat. Anz. Suppl. 160, 93-114 (1986).
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TISLJAR, U. and DENKER, H.-W.:
A sensitive assay for proleolytic activity using fluorescein-labeled gelatin coupled to Sepharose 4B as substrate.
Analytical Biochem. 152, 39-41 (1986). PubMed
TISLJAR, U. and DENKER, H.W.:
Partial purification and characterization of a trypsin-like proteinase from rabbit preimplantation uterine fluid.
Biol. Chem. Hoppe-Seyler 366, 1053-1055 (1985). PubMed PDF-Download (1,65 MB)
DENKER, H.-W., ENDERS, A.C. and SCHLAFKE, S.:
Bizarre hypertrophy of vascular endothelial cells in rhesus monkey endometrium: experimental induction and electron microscopical characteristics.
Verh. Anat. Ges. 79, Anat. Anz. Suppl. 157, 545-548 (1985). PDF-Download (1,94 MB)
DENKER, H.-W.:
Basic aspects of ovoimplantation.
In: Obstetrics and Gynecology Annual (Ralph M. Wynn, ed.) Vol. 12. Norwalk/Connecticut, Appleton-Century-Crofts, 1983, pp. 15-42. PubMed PDF-Download (12,0 MB)
DENKER, H.-W.:
Cell lineage, determination and differentiation in earliest developmental stages in mammals.
In: Problems of the Keimbahn. New Work on Mammalian Germ Cell Lineage. (W. Hilscher, ed.) (Bibliotheca anat., No. 24). Basel: S. Karger AG, 1983, ISBN: 978-3-8055-3614-1, pp. 22-58.
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MEINSHAUSEN, E. und DENKER, H.-W.:
Entwicklungsleistungen von Kaninchenembryonen trotz Hemmung der Anheftung in utero.
Verh. Anat. Ges. 77, Anat. Anz. Suppl. 154, 421-423 (1983). PDF-Download (1,16 MB)
FISCHER, B., DENKER, H.-W., BEIER, H.M. und GERDES, H.-J.:
Der Umbau der extrazellulären Blastozystenhüllen als ein empfindlicher Indikator für unphysiologische Milieubedingungen in der in-vitro-Kultur.
Verh. Anat. Ges. 77, Anat. Anz. Suppl. 154, 427-429 (1983). PDF-Download (987 KB)
DENKER, H.-W.:
Proteases of the blastocyst and of the uterus.
In: Proteins and Steroids in Early Pregnancy (H.M. Beier and P. Karlson, eds.). Berlin: Springer-Verlag, 1982, pp. 183-208. DOI: 10.1007/978-3-642-67890-5_16
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DENKER, H.-W.:
The role of blastolemmase in implantation initiation in the rabbit.
In: Cellular and Molecular Aspects of Implantation (S.R.Glasser and D.W. Bullock, eds.). New York and London: Plenum Press, 1981, pp. 415-416.
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DENKER, H.-W.:
Proteinases and implantation.
In: Embryonic Diapause in Mammals (A.P.F. Flint, M.B. Renfree and B.J. Weir, eds.). J. Reprod. Fert., Suppl. 29, 183-186 (1981). PubMed
DENKER, H.-W.:
The determination of trophoblast and embryoblast cells during cleavage in the mammal: new trends in the interpretation of the mechanisms.
Verh. Anat. Ges. 75, Anat. Anz. Suppl. 150, 445-448 (1981). PDF-Download (1,39 MB)
DENKER, H.-W.:
Embryo implantation and trophoblast invasion.
In: Cell Movement and Neoplasia (M. De Brabander et al., eds.) Oxford/New York: Pergamon Press, 1980, pp. 151-162.
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DENKER, H.-W.:
Endometrial arylamidase secretion: a sensitive parameter of steroid hormone action and of embryo-maternal interrelationships in the rabbit.
In: Steroid Induced Uterine Proteins (M. Beato, ed.) Amsterdam/New York: Elsevier/North-Holland Biomedical Press, 1980, pp. 121-131. PDF-Download (3,73 MB)
DENKER, H.-W.:
Role of proteinases in implantation.
In: Blastocyst-Endometrium Relationships (F.Leroy, C.A. Finn, A. Psychoyos and P.O. Hubinont, eds.) (Prog. Reprod. Biol., Vol. 7). Basel: S. Karger, 1980, pp. 28-42. PDF-Download (39,0 MB)
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DENKER, H.-W. and GERDES, H.-J.:
The dynamic structure of rabbit blastocyst coverings. I. Transformation during regular preimplantation development.
Anat. Embryol. 157, 15-34 (1979).
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DENKER, H.-W. and FRITZ, H.:
Enzymic characterization of rabbit blastocyst proteinase with synthetic substrates of trypsin-like enzymes.
Hoppe-Seyler’s Z. Physiol. Chem. 360, 107-113 (1979). PubMed PDF-Download (3,19 MB)
GERDES, H.-J. und DENKER, H.-W.:
Die strukturelle Entwicklung der Keimhüllen des Kaninchens vom Stadium der Blastozystenbildung bis zur Implantation.
Verh. Anat. Ges. 73, Anat. Anz. Suppl. 146, 427-434 (1979). PDF-Download (3,29 MB)
DENKER, H.-W.:
Inhibitors of trophoblast proteinases.
In: The Biology of the Fluids of the Female Genital Tract (F.K.Beller and G.F.B. Schumacher, eds.). New York/Amsterdam/Oxford: Elsevier/North-Holland, 1979, pp. 151-161. PDF-Download (4,34 MB)
DENKER, H.-W., ENG, L.A. and HAMNER, C.E.:
Studies on the early development and implantation in the cat. II. Implantation: proteinases.
Anat. Embryol. 154, 39-54 (1978).
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DENKER, H.-W., ENG, L.A., MOOTZ, U. and HAMNER, C.E.:
Studies on the early development and implantation in the cat. I. Cleavage and blastocyst formation.
Anat. Anz. 144, 457-468 (1978). PubMed PDF-Download (4,41 MB)
DENKER, H.-W.:
The role of trophoblast-dependent and of uterine proteases in initiation of implantation.
In: Human Fertilization. International Workshop Essen, July 1976 (H. Ludwig and P.F. Tauber, eds.). Stuttgart: Georg Thieme Publishers, 1978, pp. 204-214. PDF-Download (24,0 MB)
DENKER, H.-W.:
The role of trophoblastic factors in implantation.
In: Novel Aspects of Reproductive Physiology. Seventh Brook Lodge Workshop on Problems of Reproductive Physiology, 1977 (C.H. Spilman and J.W. Wilks, eds.). New York/London: Spectrum Publications, Inc., 1978 (distributed by Halsted Press, a division of John Wiley & Sons, New York etc.), pp. 181-212. PDF-Download (67,7 MB)
DENKER, H.-W.:
Implantation: The Role of Proteinases, and Blockage of Implantation by Proteinase Inhibitors.
Berlin-Heidelberg-New York: Springer-Verlag, 1977 (= Adv. Anat. Embryol. Cell Biol., Vol. 53, Fasc. 5). (Englische Fassung der Habilitationsschrift). Print-ISBN: 978-3-540-08479-2. DOI: 10.1007/978-3-642-66781-7
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DENKER, H.-W., PETZOLDT, U.:
Proteinases involved in implantation initiation in the rabbit: microdisc electrophoretic studies.
Cytobiologie (European J. Cell Biology) 15, 363-371 (1977).
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DENKER, H.-W.:
Zur Spezifität und Empfindlichkeit des Proteasen-Substratfilmtests auf Gelatinebasis. XVIII. Sympos. Ges. f. Histochemie, Bozen 1975.
Acta Histochemica, Suppl. XVIII, 153-158 (1977). PubMed PDF-Download (2,20 MB)
DENKER, H.-W. und KÜHNEL, W.:
Experimente zum Wirkungsmechanismus von Kupfer-IUDs beim Kaninchen: Lokale Beeinflussung der endometrialen Aminosäure-Arylamidase-Aktivität durch Kupfer-IUDs.
Verh. Anat. Ges. 71, Anat. Anz. Suppl. 142, 531-535 (1977). PubMed PDF-Download (1,89 MB)
DENKER, H.-W.:
Copper IUD-induced loss of endometrial arylamidase activity in the rabbit.
Biol. Reprod. 15, 519-522 (1976). DOI: 10.1095/biolreprod15.4.519
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DENKER, H.-W.:
Formation of the blastocyst: determination of trophoblast and embryonic knot.
Current Topics in Pathology (E. Grundmann und H.W. Kirsten, eds.) Vol. 62: Developmental Biology and Pathology (A. Gropp und K. Benirschke, Vol.-eds.). Berlin-Heidelberg-New York: Springer-Verlag, 1976, pp. 59-79.
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DENKER, H.-W. und STANGL, R.:
Versuche zur Lokalisierung und Abgrenzung verschiedener Aminosäure-Arylamidasen in Uterus und Blastozyste des Kaninchens.
XVII. Symp. Ges. f. Histochemie, Bozen 1974. Acta Histochemica, Suppl. XVI, 249-257 (1976). PubMed PDF-Download (3,46 MB)
DENKER, H.-W.:
Wechselbeziehungen zwischen Blastozyste und Endometrium bei der Implantation: Beeinflussung der endometrialen Aminosäure-Arylamidase-Aktivität durch die Blastozyste.
Verh. Anat. Ges. 70, Anat. Anz. Suppl. 140, 839-847 (1976). PubMed PDF-Download (3,49 MB)
DENKER, H.-W.:
Interaction of proteinase inhibitors with blastocyst proteinases involved in implantation.
In: Protides of the Biological Fluids, Proceedings of the XXIIIrd Colloquium, Brugge 1975 (H. Peeters, ed.) Oxford etc: Pergamon Press, 1976, pp. 63-68. PDF-Download (2,55 MB)
VAN HOORN, G. and DENKER, H.-W.:
Effect of the blastocyst on a uterine amino acid arylamidase in the rabbit.
J. Reprod. Fert. 45, 359-362 (1975).
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DENKER, H.-W. and HAFEZ, E.S.E.:
Proteases and implantation in the rabbit: role of trophoblast vs. uterine secretion.
Cytobiologie 11, 101-109 (1975). PubMed PDF-Download (3,03 MB)
DENKER, H.-W.:
Implantation des Kaninchenkeims im Uterus: Bedeutung von Enzymen des Embryos bzw. des Endometriums.
Verh. Anat. Ges. 69, Anat. Anz. Suppl. 138, 281-289 (1975). PubMed PDF-Download (2,92 MB)
DENKER, H.-W.:
Trophoblastic factors involved in lysis of the blastocyst coverings and in implantation in the rabbit: observations on inversely orientated blastocysts.
J. Embryol. Exptl. Morphol. 32, 739-748 (1974).
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DENKER, H.-W.:
Protease substrate film test.
Histochemistry 38, 331-338 and 39, 193 (1974). PubMed PDF-Download (908 KB, with kind permission of Springer, Heidelberg)
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DENKER, H.-W.:
Blastocyst protease and implantation: Effect of ovariectomy and progesterone substitution in the rabbit.
Acta endocr. (Kbh.) 70, 591-602 (1972). PubMed PDF-Download (25,0 MB)
DENKER, H.-W.:
Furchung beim Säugetier: Differenzierung von Trophoblast- und Embryonalknotenzellen.
Verh. Anat. Ges. 66, Anat. Anz. Suppl. 130, 267-272 (1972). PubMed PDF-Download (2,27 MB)
DENKER, H.-W.:
Enzym-Topochemie von Frühentwicklung und Implantation des Kaninchens. III. Proteasen.
Histochemie 25, 344-360 (1971). PubMed PDF-Download (2,72 MB, with kind permission of Springer, Heidelberg)
DENKER, H.-W.:
Enzym-Topochemie von Frühentwicklung und Implantation des Kaninchens. II. Glykosidasen.
Histochemie 25, 268-285 (1971). PubMed PDF-Download (2,32 MB, with kind permission of Springer, Heidelberg)
DENKER, H.-W.:
Enzym-Topochemie von Frühentwicklung und Implantation des Kaninchens. I. Glykogenstoffwechsel.
Histochemie 25, 256-267 (1971). PubMed PDF-Download (1,41 MB, with kind permission of Springer, Heidelberg)
DENKER, H.-W.:
Substratfilmtest für den Proteasennachweis.
13. Sympos. Ges. f. Histochemie (Graz 1969), Acta Histochemica, Suppl. X, 303-305 (1971). PDF-Download (976 KB)
DENKER, H.-W.:
Phosphorylase: Methode zum Nachweis im Endometrium des Kaninchens.
13. Sympos. Ges. f. Histochemie (Graz 1969), Acta Histochemica, Suppl. X, 289-292 (1971). PDF-Download (1,25 MB)
DENKER, H.-W.:
Artefakte im Amylase-Substratfilmtest.
Histochemie 21, 17-20 (1970). PubMed PDF-Download (780 KB, with kind permission of Springer, Heidelberg)
DENKER, H.-W.:
Topochemie hochmolekularer Kohlenhydratsubstanzen in Frühentwicklung und Implantation des Kaninchens.
II. Beiträge zu entwicklungsphysiologischen Fragestellungen.
Zool. Jb. Physiol. 75, 246-308 (1970). PDF-Download (23,1 MB)
DENKER, H.-W.:
Topochemie hochmolekularer Kohlenhydratsubstanzen in Frühentwicklung und Implantation des Kaninchens.
I. Allgemeine Lokalisierung und Charakterisierung hochmolekularer Kohlenhydratsubstanzen in frühen Embryonalstadien.
Zool. Jb. Physiol. 75, 141-245 (1970). PDF-Download (29,6 MB)